Body Mass Index and In-Hospital Management and Outcomes of Pulmonary Embolism: A Nationwide Analysis
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View abstract on PubMed
Summary
This summary is machine-generated.Underweight patients admitted for acute pulmonary embolism (PE) face significantly worse outcomes, including higher mortality and longer hospital stays. Normal or overweight/obese patients generally experience better results, with greater utilization of PE therapies.
Area Of Science
- Cardiology
- Pulmonary Medicine
- Health Outcomes Research
Background
- Limited data exist on the impact of body mass index (BMI) on outcomes for patients admitted with acute pulmonary embolism (PE).
- Understanding these associations is crucial for optimizing patient care and resource allocation.
Purpose Of The Study
- To investigate the relationship between body mass index (BMI) categories and clinical outcomes in adult patients hospitalized with acute pulmonary embolism (PE).
Main Methods
- Utilized the National Inpatient Sample (2016-2020) to identify adult PE admissions.
- Categorized patients into underweight (<19.9 kg/m²), normal (19.9-24.9 kg/m²), and overweight/obese (>24.9 kg/m²) BMI groups.
- Analyzed in-hospital mortality, PE therapy utilization, and resource utilization across BMI categories.
Main Results
- Over 900,000 PE admissions were analyzed; 1.8% were underweight, 70.4% normal, and 27.7% overweight/obese.
- Underweight patients were older, had higher comorbidity, and experienced increased rates of acute organ failure, bleeding, stroke, shock, mechanical ventilation, and hemodialysis.
- While underweight patients had higher mortality (7.8% vs. 3.3% in normal BMI), overweight/obese patients had lower mortality (2.2%) but received more advanced PE therapies like thrombectomy and thrombolysis.
Conclusions
- Underweight status is significantly associated with worse outcomes in acute pulmonary embolism hospitalizations compared to normal BMI.
- Overweight/obese patients, despite lower mortality, showed higher utilization of advanced PE treatments.
- These findings highlight the complex interplay between BMI and acute PE outcomes, necessitating tailored management strategies.
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