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Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Updated: Jan 17, 2026

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

Reply to: Mifamurtide in Nonmetastatic High-Grade Osteosarcoma

Emanuela Palmerini¹, Massimo Serra¹, Toni Ibrahim¹

¹Emanuela Palmerini, MD, PhD, Osteoncology, Bone and Soft Tissue Sarcomas, and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, Massimo Serra, PhD and Toni Ibrahim, MD, PhD, Osteoncology, Bone and Soft Tissue Sarcomas, and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, Javier Martín Broto, MD, PhD, Research Health Institute of Fundacion Jimenez Diaz (IIS/FJD; UAM), Madrid, Spain, Department of Medical Oncology, Fundacion Jimenez Diaz University Hospital, Madrid, Spain, University Hospital General de Villalba, Madrid, Spain.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|January 14, 2026

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No abstract available in PubMed .

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