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A new chromone from the roots of Stellera chamaejasme L
Liu Qiong1, Hong-Qian Pan1, Bai Jing-Jie1
1State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, People's Republic of China.
Abstract:
A new chromone (1), together with three known compounds (2-4), was isolated from the roots of Stellera chamaejasme L. The structure of compound 1 was elucidated by comprehensive spectroscopic analyses, including 1D and 2D NMR (HSQC, COSY, HMBC) and HR-ESI-MS. The absolute configuration was further determined by comparison of the experimental and time-dependent density functional theory (TDDFT)-calculated electronic circular dichroism (ECD) spectra. And all compounds (1-4) exhibited weak cytotoxicity against HL-60 and HeLa cell lines.
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