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Reply to Finsterer: Why HAPE Was the Most Likely Diagnosis in This Case

Yosuke Fukuda1,2, Naruhito Oda1, Kensuke Izumizaki1

  • 1Department of Medicine, Division of Respiratory Medicine, Yamanashi Red Cross Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|January 14, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
bioelectrical impedance analysisdiabetes mellitusglycemic controlhemoglobinmuscle quality

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The Hinsberg test is a method to identify primary, secondary and tertiary amines, named after its pioneer, Oscar Hinsberg. Here, amines are treated with benzenesulfonyl chloride, also known as the Hinsberg reagent, in the presence of an excess of aqueous base, followed by acidification. Based on the nature of the amines, different changes are observed.
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing sulfonyl...

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