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Gamma-aminobutyric acid effects on pituitary gonadotropin secretion
Science (New York, N.Y.)
|November 22, 1974
Abstract:
Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle-stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor.