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Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion: A Case Report
Ngoc Nguyen1, Nathan Silvera2, Jagadeesh Kumar2
1Medical Education, Philadelphia College of Osteopathic Medicine, Philadelphia, USA.
Cureus
|January 15, 2026
Summary
A rare cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) was identified in a patient. Molecular testing confirmed the diagnosis, highlighting its importance in differentiating CMTCT from other neoplasms.
Area of Science:
- Dermatopathology
- Oncology
- Molecular Pathology
Background:
- Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMTCT) is a rare neoplasm.
- CMTCT presents diagnostic challenges due to overlapping features with melanoma and clear cell sarcoma (CCS).

