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Suspected central nervous system involvement in multiple myeloma on MRI
Fabiana Andrade Melchiori1, Mette Niemann Christoffersen2, Konstantina Foufa3
1Department of Radiology, University Hospital of Southern Denmark, Aabenraa, Denmark.
Radiology Case Reports
|January 15, 2026
Summary
Central nervous system involvement in multiple myeloma (CNS-MM) is a rare complication. This case highlights unusual pituitary stalk and cerebral venous sinus thrombosis findings, emphasizing diagnostic challenges in recognizing this aggressive disease.
Area of Science:
- Neurology
- Hematology
- Oncology
Background:
- Central nervous system involvement in multiple myeloma (CNS-MM) is uncommon, typically occurring at relapse and indicating a poor prognosis.
- Extramedullary disease, including CNS involvement, can present atypically in multiple myeloma.
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