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Related Concept Videos

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Visualizing physiological sclerotic dentin via micro-computed tomography: A pilot study.

Muhammad Zaid Zainuddin1,2, Noor Shafini Mohamad3, Su Keng Tan4

  • 1Digital Dentistry Space Laboratory, Faculty of Dentistry, Universiti Teknologi MARA, Malaysia.

Imaging Science in Dentistry
|January 15, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a new 3D method using micro-CT to visualize and quantify age-related physiological dentin sclerosis in teeth. Older teeth showed increased sclerotic dentin, confirming the method

Keywords:
AgingDentinTooth RootX-Ray Microtomography

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Area of Science:

  • Dental Anatomy
  • Radiology
  • Biomaterials Science

Background:

  • Physiological dentin sclerosis is an age-related change in tooth roots, previously visualized only in 2D.
  • Understanding this phenomenon is crucial for dental diagnostics and treatment planning.

Purpose of the Study:

  • To propose and validate a novel 3D method for visualizing and quantifying physiological sclerotic dentin.
  • To utilize density-based micro-computed tomography (micro-CT) gray values for this purpose.

Main Methods:

  • Forty single-rooted premolars from the Malay male population of known chronological age were scanned using micro-CT.
  • Three-dimensional datasets were reconstructed, and volumetric analysis of root dentin was performed using FIJI (ImageJ) software.

Main Results:

  • Micro-CT successfully enabled the visualization, isolation, and quantification of high-density areas corresponding to sclerotic dentin.
  • A characteristic butterfly-shaped pattern was observed in the gray value profile.
  • Premolars from individuals aged 31-60 years showed a larger sclerotic dentin area compared to younger teeth.

Conclusions:

  • This pilot study demonstrates the feasibility of using micro-CT for 3D visualization and measurement of physiological sclerotic dentin.
  • The method's accuracy depends on micro-CT scanner capabilities and image processing software.
  • Further research with advanced micro-CT techniques is recommended to enhance image quality.