Related Experiment Video
Updated: May 3, 2026

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
Published on: February 24, 2023
Adiposity trajectories from ages 11 to 22 years: 1993 Pelotas (Brazil) birth cohort
Riceli Rodeghiero Oliveira1, Luísa Silveira da Silva1, Thaynã Ramos Flores2
1Programa de Pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brasil.
Abstract:
We examined adiposity trajectories (body mass index - BMI and body fat percentage - BF%) from ages 11 to 22 years and described them according to sex and maternal characteristics. Data were analyzed from the 1993 Pelotas (Brazil) birth cohort. BMI (n = 3,072) and BF% (n = 3,058) measurements were assessed at four time points (11, 15, 18, and 22 years). Trajectories were found using a group-based modeling approach by sex and described according to maternal characteristics using the Pearson's chi-squared test. This study found three BMI trajectories: "always adequate", "always with overweight", and "always with obesity". Approximately 40% of the cohort was classified as "always with overweight" or "always with obesity". For BF%, three trajectories were observed among males, including one with a consistently low BF% over time, whereas women's trajectories showed an increase in BF% from adolescence onward. Maternal overweight was associated with higher adiposity trajectories in both sexes. Men with higher family income and lower maternal education had a higher prevalence of high adiposity trajectories for both BMI and BF%. In women, those from lower-income backgrounds had a higher prevalence of the "always with overweight" or "always with obesity" trajectories. The adiposity trajectories of men and women belonging to the 1993 birth cohort suggest significant increases in body fat from ages 11 to 22 years, and even more pronounced upward trajectories when these youths' mothers were overweight at the beginning of this trajectory.
Related Concept Videos
Regression Toward the Mean
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Obesity
Signs of Puberty
Longitudinal Studies
Cellular Adaptation III: Hyperplasia
