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Updated: Jan 17, 2026

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Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
Published on: August 31, 2021
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Force-competition mechanisms and particle dynamics in structurally coupling-regulated cascaded microcavity optical
Optics Letters
|January 15, 2026
Summary
This study introduces a novel single-wavelength particle manipulation technique using optical tweezers. It precisely controls particle movement between capture and transport modes by tuning optical power and structural coupling.
Area of Science:
- Optofluidics
- Optical Tweezers
- Microscale Engineering
Background:
- Optical tweezers utilize light forces for particle manipulation.
- Microcavity structures offer enhanced optical field confinement.
- Controlling interactions between optical and fluidic forces is crucial for advanced microdevices.
Purpose of the Study:
- To develop a single-wavelength particle manipulation method in optofluidic systems.
- To explore the competition between optical and fluidic forces for precise particle control.
- To demonstrate controlled transitions between particle capture and transportation modes.
Main Methods:
- Utilizing a cascaded microcavity optical tweezer structure.
- Tuning structural coupling and optical power to create a tunable competitive state.
- Employing numerical analysis and experimental validation in a critical-coupling state.
Main Results:
- Established a tunable mechanical competitive state by adjusting coupling and power.
- Demonstrated controlled transitions of particles between capture and transportation modes.
- Validated the approach experimentally in a power-sensitive critical-coupling regime.
Conclusions:
- The developed method enables precise, non-contact particle manipulation in optofluidic microsystems.
- Coordinated tuning of structural coupling and optical power is key to controlling particle dynamics.
- This work presents a new pathway for advanced optofluidic applications.

