Is Preoperative Antimicrobial Prophylaxis Necessary in Testicular Torsion Surgery? Results from the National Surgical
Alexandra Stone1, Maithili Gopalakrishnan1, Anthony Tracey1
1Department of Urology, SUNY Upstate Medical University, Syracuse, New York, United States.
Insights
Surgical antimicrobial prophylaxis (SAP) showed limited impact on testicular torsion surgery (TTS) outcomes. This study found no significant difference in postoperative complications like surgical site infections or readmissions between patients who received SAP and those who did not.
Area of Science:
- Pediatric Surgery
- Surgical Outcomes Research
- Infectious Disease Prevention
Background:
- Testicular torsion surgery (TTS) is a critical pediatric urological emergency.
- Surgical antimicrobial prophylaxis (SAP) is commonly used to prevent postoperative complications.
- The efficacy of SAP in TTS has not been extensively studied using large-scale datasets.
Purpose of the Study:
- To evaluate the impact of surgical antimicrobial prophylaxis (SAP) on postoperative outcomes in patients undergoing testicular torsion surgery (TTS).
- To analyze complication rates, including surgical site infection (SSI), 30-day readmission, and 30-day reoperation.
- To utilize the National Surgical Quality Improvement Program Pediatric (NSQIP-P) database for comprehensive outcome assessment.
Main Methods:
- Retrospective analysis of the 2021-2023 NSQIP-P database for all TTS cases.
- Exclusion of patients with unrecorded SAP administration data (n=2,725).
- Comparison of postoperative events between patients who received SAP (+ SAP, n=322) and those who did not (- SAP, n=292).
Main Results:
- No surgical site infections (SSI) were observed in the + SAP group; however, there were instances of 30-day readmission and reoperation.
- In the - SAP group, one deep incisional SSI and readmission occurred, with no 30-day reoperations.
- Statistical analysis revealed no significant differences in primary outcomes (SSI, 30-day readmission, 30-day reoperation) between the SAP and no-SAP groups.
Conclusions:
- This is the first study to assess SAP's impact in torsion-reduction surgeries using the NSQIP-P database.
- Postoperative complication rates following TTS are generally low.
- The findings suggest limited utility of routine SAP for testicular torsion surgery, despite its continued use.
Objective:
This study aimed to evaluate the impact of surgical antimicrobial prophylaxis (SAP) on testicular torsion surgery (TTS) postoperative outcomes using data from the National Surgical Quality Improvement Program Pediatric (NSQIP-P). Across multiple studies, NSQIP-P has proven increased sensitivity in recording postoperative complications compared with similar databases.
Methods:
The 2021-2023 NSQIP-P participant user and SAP files were queried for all TTSs. Patients with unrecorded SAP administration data (n = 2,725) were excluded. Postoperative events were then compared between subjects who did or did not receive SAP. Primary outcomes included rates of surgical site infection (SSI), 30-day readmission, and 30-day reoperation. SPSS statistical software was used to perform comparative statistical analyses between groups.
Results:
A total of 614 patients were included in the study and divided into Group 1 (+SAP, n = 322) and Group 2 (-SAP, n = 292). In the +SAP group, there was no observation of SSI, but one case resulted in 30-day readmission and reoperation. Another 30-day readmission and 30-day reoperation were noted, as well. In the -SAP, there was one observation of a deep incisional SSI who was readmitted. There were no 30-day reoperations in this group. There was no statistical significance in outcomes between the two groups.
Conclusion:
To date, this is the first study assessing the impact of SAP in torsion-reduction surgeries using the NSQIP-P database. There is a low frequency of postoperative complications with this procedure. Our study suggests limited utility of SAP with this surgery despite continued use.
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