[Risk factors and prognosis of heart block after transcatheter closure of perimembranous ventricular septal defect in children]
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View abstract on PubMed
Summary
This summary is machine-generated.Transcatheter closure of perimembranous ventricular septal defects (pmVSD) in children can lead to heart block. Higher occluder-to-defect ratios, thin-waist occluders, and longer procedures increase risk, while specific device placement may be protective.
Area Of Science
- Cardiology
- Pediatric Cardiology
- Medical Devices
Background
- Transcatheter closure is a common treatment for perimembranous ventricular septal defects (pmVSD) in children.
- Heart block is a potential complication following this procedure.
Purpose Of The Study
- To identify risk factors for heart block after pmVSD transcatheter closure in children.
- To evaluate the long-term prognosis of postprocedural heart block.
Main Methods
- Retrospective cohort study of 1,427 children undergoing pmVSD transcatheter closure.
- Analysis of demographic, procedural, and follow-up data.
- Multivariable logistic regression to identify risk factors for heart block occurrence and persistence.
Main Results
- 20.7% of patients developed postprocedural heart block, most commonly incomplete right bundle branch block.
- Independent risk factors for heart block included higher occluder-to-defect ratio, thin-waist occluders, and longer procedure duration.
- Deployment of the occluder's left disk within aneurysmal tissue was protective.
- 161 of 295 patients with heart block recovered normal conduction; 134 had persistent block.
Conclusions
- Specific procedural factors increase the risk of heart block following pmVSD transcatheter closure in children.
- While prognosis is generally favorable, long-term follow-up is crucial due to potential late-onset or recurrent heart block.
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