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Skin disease diagnostics through federated transfer learning on heterogeneous data.
Shikha Sharma1, Ruchi Mittal2, Nitin Goyal3
1Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, India.
Scientific Reports
|January 15, 2026
Summary
This study introduces a privacy-preserving federated transfer learning model for accurate skin disease diagnosis. The machine learning approach achieves high accuracy, enhancing early detection and treatment effectiveness.
Area of Science:
- Dermatology and Artificial Intelligence
- Medical Informatics
- Computational Health
Background:
- Skin diseases present significant physical and mental health challenges globally.
- Accurate and timely diagnosis is critical for effective dermatological treatment.
- Machine learning (ML) and deep learning (DL) show promise for enhancing diagnostic accuracy but require large datasets.
Purpose of the Study:
- To develop a privacy-preserving federated transfer learning framework for skin disease diagnosis.
- To address data shortages and privacy concerns in healthcare data sharing for ML models.
- To improve the efficiency and accuracy of dermatological diagnostic tools.
Main Methods:
- Utilized transfer learning with a dense neural network (DNN) for initial skin disease detection.
- Employed pre-trained architectures for feature extraction, followed by DNN classification.
- Integrated federated learning (FL) to train models across distributed nodes while preserving data privacy.
- Combined FL with transfer learning to create a secure and effective diagnostic ecosystem.
Main Results:
- The proposed feature extraction with federated learning model achieved high cross-validation accuracy: 99.528% on IID and 99.689% on non-IID databases.
- Demonstrated the capability to create efficient, lightweight models suitable for resource-constrained environments.
- Showcased ensemble learning's ability to enhance edge device performance.
Conclusions:
- Federated transfer learning offers a powerful, privacy-preserving solution for skin disease diagnosis.
- The developed model provides an efficient and accurate tool for modern healthcare settings.
- This approach effectively overcomes data limitations and privacy regulations in medical AI.

