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Updated: Jan 18, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
[Addictions : what's new in 2025]
Daniele Zullino1, Louise Penzenstadler1, Tiphaine Robet1
1Service d'addictologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Abstract:
The field of addiction medicine is rapidly evolving due to shifting drug markets and emerging patterns of use. In Switzerland, the possible arrival of highly potent synthetic opioids highlights the need for interprofessional preparedness, particularly through wider training in naloxone use. At the same time, the rise in recreational ketamine use brings an underestimated urological complication: ketamine-induced cystitis, whose early detection is crucial. Growing digitalisation also fosters compulsive pornography use, where craving plays a key role; new tools such as the PCE-S scale help to better assess these mechanisms. Together, these trends call for strengthened monitoring, prevention, and adaptive clinical strategies.
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