Negative Pressure Wound Therapy in an Immunocompromised Child: A Case Report From a Resource-Limited Setting in Ghana

Matilda Mawusi Kodjo1, Kennedy Kofi Kru1,2, Belinda Dziedzorm Korley3

  • 1Department of Nursing University of Health and Allied Sciences Ho Ghana.

Clinical Case Reports
|January 16, 2026
PubMed

Insights

Negative pressure wound therapy (NPWT) can rapidly heal large septic wounds, even in immunocompromised patients. This innovative approach shows promise for faster recovery and reduced hospital stays.

Area of Science:

  • Medicine
  • Wound Healing
  • Medical Devices

Background:

  • Large septic wounds pose significant treatment challenges.
  • Effective wound management is crucial for patient recovery and reducing healthcare burden.
  • Standard treatments may fail, necessitating alternative approaches.

Purpose of the Study:

  • To evaluate the efficacy of an improvised vacuum-assisted closure device for treating a large septic wound.
  • To assess the impact of negative pressure wound therapy on wound healing in an immunocompromised pediatric patient.
  • To determine if patient immune status affects healing outcomes with negative pressure wound therapy.

Main Methods:

  • A case study involving an 8-year-old immunocompromised girl with a large septic left thigh wound.
  • Utilization of an improvised vacuum-assisted closure device due to unavailability of the standard device.
  • Application of negative pressure wound therapy for wound healing promotion.

Main Results:

  • Significant wound improvement observed within the first week of treatment.
  • Rapid formation of healthy granulation tissue, closing the wound by the third day.
  • Successful healing despite the patient's immunocompromised status.

Conclusions:

  • Negative pressure wound therapy can accelerate the healing of large wounds, exceeding expectations.
  • Patient immune status may not be a limiting factor in achieving rapid wound healing with NPWT.
  • This therapy offers potential for shorter hospital stays and decreased staff workload.

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