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Tranexamic acid induced seizure during spine surgery: A case report

Thomas J Ryan1, Christopher Lucasti2, Danielle E Chipman1

  • 1Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.

International Journal of Surgery Case Reports
|January 16, 2026
PubMed
Summary

Tranexamic acid (TXA) effectively reduces blood loss in spine surgery but carries a rare risk of seizures. This case highlights the importance of monitoring patients for adverse events like seizures following TXA administration.

Keywords:
Case reportPerioperative seizureSpine surgeryTranexamic acid

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