A Randomized Controlled Trial Comparing Intrathecal 0.5% Hyperbaric Levobupivacaine and 0.75% Hyperbaric Ropivacaine...

Area of Science:

• Anesthesiology
• Obstetric Anesthesia
• Pharmacology

Background:

• Spinal anesthesia is commonly used for cesarean sections.
• Levobupivacaine and ropivacaine are local anesthetics used for spinal anesthesia.
• Comparing their efficacy and safety in parturients is crucial.

Purpose of the Study:

• To compare intrathecal levobupivacaine and ropivacaine in parturients undergoing elective cesarean section.
• To evaluate sensory and motor block profiles, hemodynamic stability, neonatal outcomes, and adverse effects.

Main Methods:

• Randomized, double-blind, controlled trial with 66 parturients.
• Groups received either levobupivacaine or ropivacaine.
• Standardized protocols assessed block characteristics, hemodynamics, and Apgar scores.

Main Results:

• Levobupivacaine induced faster, longer sensory and motor blockade.
• Ropivacaine showed better hemodynamic stability and quicker motor recovery.
• Ropivacaine group had higher Apgar scores, with all outcomes clinically acceptable.

Conclusions:

• Levobupivacaine is suitable for extended anesthesia and analgesia.
• Ropivacaine offers superior hemodynamic stability, faster motor recovery, and better neonatal outcomes.
• Choice depends on clinical priorities; both are safe and effective for cesarean section spinal anesthesia.