Radiologic Features of Curvilinear and Tubulonodular Pericallosal Lipomas: Two Case Reports

Pericallosal lipomas or lipomas of the corpus callosum are rare, benign, fat-containing congenital brain lesions. They may occur in isolation or be associated with corpus callosum dysgenesis or agenesis. Therefore, they have a broad clinical presentation, ranging from being totally asymptomatic to having seizures, motor deficits, or headaches. Imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) are key to diagnosis, allowing recognition of two morphological subtypes: tubulonodular and curvilinear. In this article, we report two cases. The first concerns a 35-year-old woman evaluated for helmet-like headaches, in whom a brain MRI demonstrated a curvilinear lipoma of the corpus callosum. The second case concerns a 33-year-old man with headaches following a benign trauma, in whom CT and MRI identified a tubulonodular corpus callosum lipoma. These cases emphasize the significance of imaging in distinguishing between these two forms.