Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Classification System01:24

Microbial Classification System

987
Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...
987
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

987
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
987
Microbial Growth Media01:27

Microbial Growth Media

1.3K
Microbial growth media are essential tools in microbiology, providing the nutrients and conditions necessary to cultivate and study microorganisms. These media are categorized by their composition, consistency, and functional roles, enabling researchers to investigate microbial physiology, behavior, and interactions.Types and Consistencies of Growth MediaGrowth media can be solid, liquid, or semisolid. Solid media, often agar-based, allow visible colony growth for isolation and enumeration.
1.3K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

599
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
599
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

517
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
517
Microbial Morphologies01:29

Microbial Morphologies

1.9K
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

iMPI: An Integrative Database for MicroProteins Encoded by Intron Retention in Tumors.

Proteomics·2026
Same author

pKAKA: a protein language model for prioritizing kinase-disrupting variants in diseases.

Journal of genetics and genomics = Yi chuan xue bao·2026
Same author

Porphyromonas gingivalis-induced HuR upregulation suppresses SLC39A10-derived hsa_circ_0057552 in esophageal squamous cell carcinoma.

Microbes and infection·2025
Same author

Inferring kinase-phosphosite regulation from phosphoproteome-enriched cancer multi-omics datasets.

Briefings in bioinformatics·2025
Same author

m6A2Circ: A comprehensive database for decoding the regulatory relationship between m6A modification and circular RNA.

Computational and structural biotechnology journal·2025
Same author

[Ag<sub>2</sub>Se nanoparticles suppress growth of murine esophageal cancer allograft in mice by eliminating <i>Porphyromonas gingivalis</i>].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2025

Related Experiment Video

Updated: Jan 18, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
09:49

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

Published on: October 31, 2019

23.1K

BodyMeta: A comprehensive database for microbes under various pathological and physiological conditions.

Dong Zhang1, Jiamin Hu2, Bianli Gu3

  • 1Department of Oncology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province 510080, China.

Computational and Structural Biotechnology Journal
|January 16, 2026
PubMed
Summary

BodyMeta is a new database that expands on gutMEGA, cataloging microbial data from 1261 studies across 31 body sites. This resource details microbial changes in health and disease, aiding human health research.

Keywords:
DatabaseHuman healthMetagenomicsMicrobiotaPathologyPhysiology

More Related Videos

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

19.9K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

827

Related Experiment Videos

Last Updated: Jan 18, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
09:49

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

Published on: October 31, 2019

23.1K
Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

19.9K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

827

Area of Science:

  • Microbiology
  • Bioinformatics
  • Genomics

Background:

  • Microbial communities in various body sites are crucial for human health.
  • Significant alterations in these microbiomes occur during physiological and pathological states.
  • A comprehensive database is needed to study these microbiome changes across diverse conditions and body sites.

Purpose of the Study:

  • To develop BodyMeta, an expanded metagenomic database of microbial communities from diverse human body sites.
  • To integrate data from a significantly larger number of studies compared to previous resources.
  • To provide a unified resource for investigating microbial roles in both health and disease.

Main Methods:

  • Developed BodyMeta by upgrading and expanding the gutMEGA database.
  • Integrated data from 1261 studies, including literature-based and raw sequencing datasets (whole-genome and 16S amplicon).
  • Categorized 1842 conditions (966 pathological, 879 physiological) across 31 body sites, annotating microbial content, diversity, biomarkers, and functions.

Main Results:

  • BodyMeta incorporates 1261 studies, a substantial increase from 182.
  • Cataloged 1842 conditions across 31 body sites, with pathological conditions classified using MeSH terms.
  • Annotated microbial taxa (59010 from literature, 40657 from raw data) and compiled extensive experimental and literature information.

Conclusions:

  • BodyMeta serves as a comprehensive, publicly accessible resource for metagenomic research.
  • Facilitates the study of microbial community alterations in diverse physiological and pathological conditions.
  • Supports advancements in understanding the link between the microbiome and human health.