Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationships between brain functional connectivity and resting cardiac autonomic profiles in functional neurological disorder: A pilot study.

NeuroImage. Clinical·2026
Same author

Clinical and Pathological Progression of Awareness Trajectories in Preclinical Alzheimer's Disease.

medRxiv : the preprint server for health sciences·2026
Same author

Web-Based Acceptance and Commitment Therapy Tobacco Cessation Program for Veterans With Mental Health Disorders: Adaptation and Usability Testing.

JMIR formative research·2026
Same author

Functional Neurologic Symptoms in Multiple Sclerosis: Estimated Prevalence and Associated Comorbidities.

Neurology. Clinical practice·2026
Same author

Functional Connectivity Predictors and Mechanisms of Symptom Change in Functional Neurological Disorder.

medRxiv : the preprint server for health sciences·2026
Same author

Neuronal Distribution of Tau Pathology, Microglial Gene Expression Trajectories, and Resilience to Alzheimer disease.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Jun 15, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

15.7K

Relationships Between Brain Functional Connectivity and Resting Cardiac Autonomic Profiles in Functional Neurological

Cristina Bleier, Andrew J Guthrie, Jessica Ranford

    Medrxiv : the Preprint Server for Health Sciences
    |January 16, 2026
    PubMed
    Summary

    This study found that in functional neurological disorder (FND), autonomic nervous system function, specifically heart rate variability, is linked to brain network connectivity in key areas. These findings highlight the interplay between the body

    More Related Videos

    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
    08:23

    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

    Published on: November 13, 2016

    11.7K
    Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
    07:13

    Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

    Published on: May 27, 2020

    7.1K

    Related Experiment Videos

    Last Updated: Jun 15, 2026

    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
    10:43

    Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

    Published on: July 1, 2014

    15.7K
    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
    08:23

    A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

    Published on: November 13, 2016

    11.7K
    Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
    07:13

    Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

    Published on: May 27, 2020

    7.1K

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Autonomic Physiology

    Background:

    • Functional Neurological Disorder (FND) is linked to altered brain functional networks.
    • The relationship between peripheral autonomic function and brain architecture in FND is not well understood.
    • This pilot study investigates cardiac autonomic metrics and resting-state functional connectivity (rsFC) in FND.

    Purpose of the Study:

    • To examine associations between cardiac autonomic metrics (Interbeat Interval [IBI] and Heart Rate Variability [HRV]) and rsFC in females with FND.
    • To compare these associations in FND patients with age-matched female psychiatric controls (PCs).

    Main Methods:

    • Twenty females with FND and 23 PCs underwent questionnaires, 10-min resting photoplethysmography, and resting-state fMRI.
    • IBI and HRV metrics were extracted from physiological recordings.
    • Whole-brain rsFC was quantified using weighted-degree centrality, with analyses adjusting for covariates and applying cluster-wise correction.

    Main Results:

    • No significant differences in IBI or HRV were found between FND and PC groups.
    • In FND, shorter IBI correlated with increased rsFC in supplementary motor area (SMA) and frontal regions.
    • In FND, higher HRV correlated with decreased rsFC in SMA, mid-cingulate cortex, amygdala, insula, and orbitofrontal cortex; associations were more localized in PCs.

    Conclusions:

    • Individual differences in resting autonomic physiology in FND are associated with the centrality of brain regions within central autonomic, salience, and allostatic-interoceptive networks.
    • The interplay between autonomic physiology and brain network architecture may be a significant factor in FND.