Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs01:20

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs

228
Body:Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to...
228

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety in Robotic Kidney Transplant for All-Comers: Does Body Mass Index Need to be Considered?

Kidney360·2026
Same author

Evaluating Barriers to Kidney Transplantation in the United States.

Journal of the American Society of Nephrology : JASN·2026
Same author

Largest Year-on-Year Decline in Deceased Donation in United States History.

Clinical transplantation·2026
Same author

A Pre-Kidney Transplant Blood-Based Next-Generation Sequencing Assay to Predict Early Acute Rejection.

Kidney360·2026
Same author

Measuring What Matters: Days Alive and Out of Hospital and Health Care Utilization in Kidney Transplantation.

Kidney360·2026
Same author

Newly Designed Expedited Allocation Pathways Cannot Be Expected to Rely on Data That Does Not Currently Exist.

Kidney360·2026

Related Experiment Video

Updated: Jan 18, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

907

Newly designed expedited allocation pathways cannot be expected to rely on data that does not currently exist.

Cameron D Ekanayake, Syed A Husain, Miko E Yu

    Medrxiv : the Preprint Server for Health Sciences
    |January 16, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Allocation out of sequence (AOOS) documentation for discarded kidneys is rare and inconsistent. This hinders accurate assessment of AOOS impact on kidney transplant utility and requires improved reporting for future pathway evaluations.

    More Related Videos

    Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
    08:58

    Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

    Published on: October 17, 2025

    611
    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
    06:55

    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

    Published on: January 8, 2020

    15.1K

    Related Experiment Videos

    Last Updated: Jan 18, 2026

    Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
    03:08

    Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

    Published on: October 3, 2025

    907
    Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
    08:58

    Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

    Published on: October 17, 2025

    611
    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
    06:55

    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

    Published on: January 8, 2020

    15.1K

    Area of Science:

    • Transplantation Science
    • Organ Procurement
    • Health Data Analytics

    Background:

    • Allocation out of sequence (AOOS) facilitates expedited kidney placement by organ procurement organizations (OPOs), bypassing standard matching.
    • Accurate assessment of AOOS impact on organ utility requires documentation of all attempts, including those not resulting in transplant.
    • Current data capture for AOOS in discarded kidneys may be insufficient for comprehensive analysis.

    Purpose of the Study:

    • To assess the frequency and consistency of AOOS documentation in discarded kidneys.
    • To identify potential data-capture deficiencies in reporting AOOS events.
    • To highlight the need for improved AOOS reporting for evaluating expedited allocation pathways.

    Main Methods:

    • Utilized Scientific Registry of Transplant Recipients (SRTR) Potential Transplant Recipient (PTR) offer data from 2021-2024.
    • Identified match-runs involving at least one discarded kidney.
    • Defined AOOS per Health Resources and Services Administration (HRSA) guidelines and stratified data by recovery/disposition patterns, focusing on 2024.

    Main Results:

    • In 2024, only 4.3% of match-runs with discarded kidneys showed evidence of AOOS documentation.
    • AOOS-coded discards varied significantly across OPOs, ranging from 0.0% to 17.1% (median 3.9%).
    • Documentation of AOOS for discarded kidneys is infrequent and inconsistent across OPOs.

    Conclusions:

    • Significant data-capture deficiencies exist in documenting AOOS efforts for discarded kidneys.
    • Current reporting practices impede accurate evaluation of AOOS effectiveness.
    • Enhanced and consistent AOOS reporting is crucial for the successful implementation and assessment of future expedited organ allocation strategies.