Clinical Outcomes in Young Patients Undergoing Percutaneous Coronary Intervention
Isaac Park1, Millie Watkins1, Diem Dinh2
1Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia.
Summary
Young adults undergoing percutaneous coronary intervention (PCI) have low mortality, but comorbidities like diabetes and kidney disease increase long-term risks. Improved secondary prevention is crucial for these high-risk patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- Young adults undergoing percutaneous coronary intervention (PCI) are often considered low-risk.
- Limited long-term outcome data exist for this demographic.
- Identifying predictors of adverse events is key to improving care.
Purpose of the Study:
- To determine the incidence and predictors of 12-month mortality.
- To evaluate major adverse cardiovascular events (MACE) within 30 days.
- To analyze a contemporary Australian cohort of young PCI patients.
Main Methods:
- Analysis of data from the Victorian Cardiac Outcomes Registry (VCOR) (2014-2023).
- Inclusion of patients aged 18-55 years undergoing PCI.
- Exclusion of patients with out-of-hospital cardiac arrest or cardiogenic shock.
Main Results:
- 12-month mortality was 1.0% across all age subgroups.
- Predictors of mortality included low eGFR, reduced ejection fraction, diabetes, and female sex.
- Lower dual antiplatelet therapy use, femoral access, and bare-metal stents were noted in deceased patients.
Conclusions:
- 12-month mortality after PCI in young adults is low.
- Comorbidities like diabetes, CKD, and LV dysfunction are linked to worse outcomes.
- Enhanced secondary prevention is vital for high-risk young patients post-PCI.
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