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Related Concept Videos

Organization of the Nervous System01:13

Organization of the Nervous System

The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Organization of the Brain01:30

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

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Related Experiment Video

Updated: Jun 25, 2026

Dissection of Hippocampal Dentate Gyrus from Adult Mouse
07:42

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Published on: November 17, 2009

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Japan Brain Bank Net (JBBN).

Masaki Takao1

  • 1Department of Clinical Laboratory and Internal Medicine, National Center of Neurology and Psychiatry (NCNP). National Center Hospital, Tokyo, Japan.

Psychiatry and Clinical Neurosciences
|January 16, 2026
PubMed
Summary

The Japan Brain Bank Net (JBBN) facilitates neurological and psychiatric research by storing and providing brain tissue samples. This network aims to advance disease understanding and treatment development through standardized diagnoses and emerging research methodologies.

Keywords:
JBBNautopsybrain bankdigitized imagesneuropathology

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Last Updated: Jun 25, 2026

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Area of Science:

  • Neurology
  • Psychiatry
  • Pathology

Background:

  • Autopsies are crucial for determining causes of death and advancing understanding of neurological and psychiatric disorders.
  • Body donation for autopsy serves various expectations, including disease treatment development and cause investigation.
  • Brain banks are essential for storing biological samples for future medical research.

Purpose of the Study:

  • To introduce the Japan Brain Bank Net (JBBN) and its role in supporting neurological and psychiatric research.
  • To highlight JBBN's functions beyond traditional tissue storage, including standardized neuropathological diagnoses.
  • To outline JBBN's initiatives in adapting to emerging research methodologies and technologies.

Main Methods:

  • Establishment and expansion of a national network of 19 participating institutions.
  • Standardization of neuropathological diagnoses across the network.
  • Development of infrastructure for storing tissue for advanced research, including AI applications and digital imaging.

Main Results:

  • JBBN currently comprises 19 institutions dedicated to brain tissue preservation and research support.
  • The network provides standardized neuropathological diagnoses, enhancing research reliability.
  • JBBN is actively developing capabilities for advanced research, including AI and digital pathology.

Conclusions:

  • The Japan Brain Bank Net (JBBN) is a vital infrastructure supporting current and future neuropathological research.
  • JBBN's initiatives in digitization, AI, and database development position it at the forefront of research support.
  • The network aims to foster a sustainable brain bank system for next-generation scientific discovery.