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Related Experiment Video

Updated: Jan 18, 2026

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
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Flexible surface-enhanced Raman scattering active substrates based on carbon materials.

Ling Zhu1, Rong Yang1, Yang Cao2

  • 1College of Materials Science and Engineering, Nanjing Tech University, No.30 Puzhu South Road, Jiangbei New Area, Nanjing, Jiangsu, 211816, China.

Talanta
|January 16, 2026
PubMed
Summary

Flexible carbon-based substrates offer superior SERS detection for molecules. This review covers advances, mechanisms, and applications in food safety, environmental monitoring, and biomedicine.

Keywords:
ApplicationsComposite structure designDopingFlexible carbon materialsPerspectivesSurface-enhanced Raman scattering

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Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Nanotechnology

Background:

  • Surface-enhanced Raman scattering (SERS) enables sensitive, label-free detection of low-concentration molecules.
  • Conventional SERS substrates (rigid, paper, polymer) have limitations.
  • Flexible carbon-based SERS substrates offer enhanced mechanical strength, chemical stability, sensitivity, biocompatibility, and fluorescence quenching.

Purpose of the Study:

  • To systematically review recent advances in flexible carbon-based SERS substrates.
  • To discuss SERS enhancement mechanisms and the properties of pure carbon materials.
  • To explore strategies for improving SERS performance and review applications.

Main Methods:

  • Review of literature on flexible carbon-based SERS substrates.
  • Categorization of pure carbon materials based on dimensions and SERS activity.
  • Discussion of enhancement strategies like doping and composite structure construction.
  • Analysis of applications in food safety, environmental monitoring, and biomedicine.

Main Results:

  • Flexible carbon-based SERS substrates exhibit significant advantages over conventional options.
  • Doping and composite structures are key strategies to enhance SERS responsiveness.
  • These substrates show promising applications across diverse fields.

Conclusions:

  • Flexible carbon-based SERS substrates represent a rapidly advancing area with significant potential.
  • Further research is needed to address current challenges and explore future trends.
  • These materials are poised to impact sensitive molecular detection in various critical applications.