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Biophysical characterisation of mRNA structure and its impact on integrity analysis by liquid chromatography and

Mayada Elgohary1, Alexandra L J Webb2, Joseph C Ward3

  • 1Analytical Sciences, BioPharmaceuticals Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom.

Journal of Chromatography. A
|January 16, 2026
PubMed

Keywords:
Capillary gel electrophoresisIon-pair reversed-phase HPLCMass photometrySHAPEmRNA higher order structuresmRNA post-main peaksmRNA purity

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