Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.1K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.1K
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

313
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
313

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dichography: two-frame ultrafast imaging from a single diffraction pattern.

Nature communications·2026
Same author

Hyperintense FLAIR signal in the anterior cranial fossa.

Nature communications·2026
Same author

Generalizable spinal cord multiple sclerosis lesion segmentation across MRI contrasts, protocols, and centers.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Fine Tuning of the Arrangement of Non-Close-Packed Structures: Specific Ion Effects of Lanthanide Cations.

ACS omega·2026
Same author

Challenges in Controlled Doping of NaMnF<sub>3</sub>:Yb<sup>3<b>+</b></sup> , Er<sup>3<b>+</b></sup> Nanoparticles.

ACS omega·2026
Same author

A Retrospective Evaluation of Ocrelizumab and Rituximab Discontinuation in a Real-World Patient Cohort.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

CT-Guided Epidural Blood Patch for Postoperative Lumbar Cerebrospinal Fluid Leak: A Case Series and Clinical Outcomes.

AJNR. American journal of neuroradiology·2026
Same journal

Clinical Outcomes of Isolated Subarachnoid Hemorrhage after Mechanical Thrombectomy.

AJNR. American journal of neuroradiology·2026
Same journal

Validation of an Automated ASPECTS Software via a Multi-Reader Multi-Case Clinical Reader Study.

AJNR. American journal of neuroradiology·2026
Same journal

Gender Trends in Authorship Across Neuroradiology Journals (2016-2025).

AJNR. American journal of neuroradiology·2026
Same journal

Outcomes of Endovascular Treatment in Large Vessel Occlusions Due to Intracranial Atherosclerotic Disease: A Systematic Review and Updated Meta-Analysis of 11,326 Patients.

AJNR. American journal of neuroradiology·2026
Same journal

Quantitative Impact of T1 Subtraction Maps on Enhancing Component Delineation and Measured Volumes in Minimally Enhancing Pediatric Brain Tumors.

AJNR. American journal of neuroradiology·2026
See all related articles

Related Experiment Video

Updated: Jan 18, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

5.0K

C-DIR: Double Inversion Recovery with Controlled Artifact Suppression in Brain MRI.

Alexander Jaffray1,2, Christina Graf1,2,3, Armin Rund2

  • 1From the Department of Physics and Astronomy (A.J., C.G., A. Rauscher), University of British Columbia, Vancouver British Columbia, Canada.

AJNR. American Journal of Neuroradiology
|January 16, 2026
PubMed
Summary
This summary is machine-generated.

Controlled Double Inversion Recovery (C-DIR) MRI uses robust inversion pulses to reduce artifacts caused by magnetic field inhomogeneities. This technique improves image quality and contrast-to-noise ratio (CNR) for better visualization of tissues like cerebrospinal fluid (CSF).

More Related Videos

Best Current Practice for Obtaining High Quality EEG Data During Simultaneous fMRI
10:35

Best Current Practice for Obtaining High Quality EEG Data During Simultaneous fMRI

Published on: June 3, 2013

33.3K
Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

15.4K

Related Experiment Videos

Last Updated: Jan 18, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

5.0K
Best Current Practice for Obtaining High Quality EEG Data During Simultaneous fMRI
10:35

Best Current Practice for Obtaining High Quality EEG Data During Simultaneous fMRI

Published on: June 3, 2013

33.3K
Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

15.4K

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Physics
  • Neuroimaging

Background:

  • Double Inversion Recovery (DIR) MRI suppresses cerebrospinal fluid (CSF) and white matter (WM) using two inversion pulses.
  • Field inhomogeneities (B0 and RF) can cause inadequate inversion, leading to artifacts and reduced image quality.
  • Existing DIR techniques are susceptible to these artifacts, limiting diagnostic accuracy.

Purpose of the Study:

  • To develop a DIR MRI sequence with inversion pulses robust against B0 and RF field inhomogeneities.
  • To improve the reliability and quality of DIR imaging in the presence of magnetic field variations.

Main Methods:

  • Developed Controlled DIR (C-DIR) using optimal control theory for inversion pulse design.
  • Incorporated robustness against field inhomogeneities into the pulse optimization cost functional.
  • Acquired 3T MRI images in 14 participants (healthy, MS, concussion, WMH) and assessed artifacts and lesion visibility.

Main Results:

  • C-DIR demonstrated improved inversion and artifact removal in the presence of field inhomogeneities.
  • Significant increases in Contrast-to-Noise Ratio (CNR) were observed (e.g., 102% between brainstem and CSF, p<0.001).
  • Signal-to-Noise Ratio (SNR) in cortical gray matter showed a trend towards improvement with C-DIR (p=0.07).

Conclusions:

  • Robust RF pulse design in C-DIR significantly enhances DIR MRI quality.
  • The technique effectively reduces artifacts and improves CNR, leading to better tissue contrast.
  • C-DIR offers a more reliable method for DIR imaging, especially in challenging magnetic field conditions.