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Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
505
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

418
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
418
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
439
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
376
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

651
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
651
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

802
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Acute oesophageal necrosis: single centre experience.

Şehmus Ölmez1, Duran Deha Çetin2, Mustafa Harı2

  • 1University of Health Sciences,, Adana City Training and Research Hospital, Department of Gastroenterology, Adana, Türkiye. drsehmusolmez@gmail.com.

BMC Gastroenterology
|January 16, 2026
PubMed
Summary
This summary is machine-generated.

Acute oesophageal necrosis (AEN) is a rare cause of upper gastrointestinal bleeding. Patient outcomes are poor, often due to comorbidities like malignancy and diabetes, highlighting the need for further research.

Keywords:
Acute oesophageal necrosisBleedingComorbidityPrognosis

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Critical Care Medicine

Background:

  • Acute oesophageal necrosis (AEN) is an uncommon but serious condition.
  • It presents as a significant cause of upper gastrointestinal bleeding (UGIB).
  • Prognosis is often poor, particularly in patients with coexisting medical conditions.

Purpose of the Study:

  • To evaluate the clinical outcomes of patients diagnosed with Acute oesophageal necrosis.
  • To identify factors influencing mortality in AEN patients.

Main Methods:

  • Retrospective analysis of patient data from Adana City Training and Research Hospital (January 2015 - July 2025).
  • Inclusion criteria: patients diagnosed with AEN via endoscopy.
  • Data evaluated: patient demographics, medical history, endoscopic findings, and outcomes.

Main Results:

  • AEN identified in 0.12% of 24,805 endoscopies.
  • Mean age 66.2 years; 51.7% female.
  • Common comorbidities: malignancy, diabetes mellitus, hypertension, coronary artery disease.
  • Presentations: haematemesis, melena.
  • Pan-oesophageal and middle oesophageal necrosis were most frequent.
  • Hospitalization mortality rate was 44.8%, primarily due to sepsis and other comorbidities, not AEN directly.

Conclusions:

  • AEN should be considered in elderly patients with UGIB and comorbidities.
  • Outcomes are significantly impacted by advanced age and conditions like malignancy, diabetes, heart disease, and cirrhosis.
  • Further multicentre, prospective studies with larger cohorts are necessary to better understand AEN.