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A Core Effector MoPce1 Is Required for the Pathogenicity of Magnaporthe oryzae by Modulating Catalase-Mediated H2O2
Jianqiang Huang1,2, Xiaomin Chen1, Huimin Bai2
1Fujian Universities Key Laboratory for Plant-Microbe Interaction, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, China.
Molecular Plant Pathology
|January 17, 2026
Summary
Magnaporthe oryzae uses the effector MoPce1 to suppress rice immunity. MoPce1 targets rice catalase (OsCATC) to disrupt reactive oxygen species (ROS) homeostasis, facilitating fungal infection.
Area of Science:
- Plant Pathology
- Molecular Plant-Microbe Interactions
- Fungal Genetics
Background:
- Plant pathogens utilize conserved core effectors (PCEs) for host colonization.
- Magnaporthe oryzae, a major rice pathogen, employs numerous effectors to infect its host.
Purpose of the Study:
- Identify key virulence factors in Magnaporthe oryzae.
- Elucidate the function and mechanism of the identified effector MoPce1 in rice-fungus interactions.
Main Methods:
- Identification and characterization of putative core effectors (PCEs).
- Localization studies of MoPce1 in host cells and fungal structures.
- Functional analysis using gene knockout and ectopic expression in rice.
- Protein-protein interaction assays to identify MoPce1 targets.
Main Results:
- MoPce1 is a crucial virulence factor essential for pathogenicity but not asexual development in M. oryzae.
- MoPce1 localizes to the biotrophic interfacial complex (BIC) and host cytoplasm.
- Ectopic expression of MoPCE1 suppressed rice blast resistance and reactive oxygen species (ROS) burst.
- MoPce1 interacts with rice catalase OsCATC, disrupting ROS homeostasis and host immunity.
Conclusions:
- MoPce1 is a novel effector targeting OsCATC to suppress plant immunity.
- MoPce1 facilitates M. oryzae infection by manipulating ROS signaling pathways.
- Understanding MoPce1-OsCATC interaction provides insights into plant-fungal pathogen strategies.
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