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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[A Case of Long-Term Survival after Pulmonary Resection for Oligometastatic Pancreatic Cancer Following Chemotherapy]
Mihono Hirota1, Takanori Konishi, Tsukasa Takayashiki
1Dept. of General Surgery, Chiba University Graduate School of Medicine.
Abstract:
51-year-old man underwent pancreatoduodenectomy(PD)for pancreatic head cancer, followed by 6 months of adjuvant chemotherapy with S-1. At 20 months postoperatively, 3 pulmonary metastases were detected. S-1 chemotherapy was administered for 16 months and no new lesions or disease progression was observed. Based on the sustained response, the patient was diagnosed with oligometastatic pancreatic cancer and staged bilateral pulmonary resections were conducted. Histopathological analysis confirmed that all the nodules were lung metastases from pancreatic cancer. At 24 months after pulmonary resection, the patient remains alive without evidence of recurrence. Currently, there are no standardized criteria for the indication or timing of surgical resection in patients with isolated pulmonary metastases from pancreatic cancer. Additionally, the definition of oligometastatic disease in pancreatic cancer remains unclear. This case suggests that pulmonary resection can lead to long-term survival in selected patients with lung metastases from pancreatic cancer. Chemotherapy for lung metastases may help identify optimal candidates for pulmonary resection.

