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[Primary Rectal Mesenteric Neuroendocrine Tumor G2-A Case Report]
Takashi Takenoya1, Kenichi Suzuki, Miho Kawaida
1Dept. of Surgery, Ogikubo Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|January 17, 2026
Summary
A rare, slow-growing neuroendocrine tumor (NET) was incidentally found in the mesorectum of an 81-year-old man. Surgical resection led to a recurrence-free outcome, highlighting NETs in mesenteric tumor differential diagnoses.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiology
Background:
- Neuroendocrine tumors (NETs) are rare neoplasms.
- Mesenteric tumors can present diagnostic challenges.
- Appendicitis can lead to incidental findings of other abdominal pathologies.
Purpose of the Study:
- To report a rare case of a primary mesenteric neuroendocrine tumor.
- To discuss the diagnostic and management challenges of mesenteric NETs.
- To emphasize the importance of considering mesenteric NETs in differential diagnosis.
Main Methods:
- Computed tomography (CT) for initial mass detection.
- Colonoscopy and endoscopic ultrasound-guided fine-needle aspiration for characterization.
- Retrospective review of prior imaging.
- Laparoscopic low anterior resection for tumor removal.
Main Results:
- An 81-year-old male presented with appendicitis and an incidentally discovered 53-mm left mesenteric mass.
- The mass was diagnosed as a grade 2 neuroendocrine tumor (NET).
- Prior imaging from 11 years earlier showed a smaller 13-mm mass in the same location, indicating slow growth.
- Laparoscopic resection was successful, with no recurrence at 6 months.
Conclusions:
- Primary mesenteric neuroendocrine tumors are rare but should be considered in the differential diagnosis of mesenteric masses.
- Slow tumor growth over a decade is possible for mesenteric NETs.
- Multimodality imaging and tissue sampling are crucial for diagnosis and management.
