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[A Case of Lower Rectal GIST Treated with Transanal Minimally Invasive Surgery(TAMIS)]
Satoshi Eguchi1, Ken Nakamura, Shinya Yamashita
1Dept. of Gastroenterological Surgery, Nippon Life Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|January 17, 2026
Summary
Transanal minimally invasive surgery (TAMIS) successfully removed a rectal GIST in an 82-year-old woman, preserving anal function. The patient remained recurrence-free two years post-operation.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Rectal gastrointestinal stromal tumors (GIST) are rare and can present diagnostic challenges.
- Surgical intervention is often necessary for rectal GIST, with a focus on preserving organ function.
Purpose of the Study:
- To evaluate the feasibility and outcomes of transanal minimally invasive surgery (TAMIS) for rectal GIST.
- To assess the efficacy of TAMIS in achieving complete tumor resection while preserving anal function.
Main Methods:
- A case report of an 82-year-old female patient diagnosed with rectal GIST.
- The patient underwent transanal minimally invasive surgery (TAMIS) using the GelPOINT® Path device.
- Tumor resection involved careful dissection from the vaginal wall, followed by layered closure.
Main Results:
- The TAMIS procedure was completed in 3 hours and 14 minutes with minimal blood loss.
- The patient experienced an uneventful postoperative recovery and was discharged on postoperative day 10.
- Two years post-surgery, the patient remained recurrence-free, despite a temporary discontinuation of adjuvant imatinib therapy due to side effects.
Conclusions:
- Transanal minimally invasive surgery (TAMIS) is a viable and effective option for rectal GIST resection, particularly in patients prioritizing anal function preservation.
- This approach offers a minimally invasive alternative to traditional surgery, with favorable short- and long-term outcomes.
