[Three Cases of Esophageal Metastasis from Breast Cancer with Different Clinical Courses Based on Treatment...

Esophageal metastasis from breast cancer is rare and seldom diagnosed before death, with no established standard treatment. We report 3 cases managed at our institution. Case 1:A 78-year-old woman previously underwent surgery for invasive ductal carcinoma(ER+, PgR+, HER2-)at the age of 65. Eight years postoperatively, the first recurrence occurred, followed by progressive dysphagia 5 years later, leading to the diagnosis of esophageal metastasis. Case 2:A 63-year-old woman had surgery at age 48 for invasive ductal carcinoma(ER+, PgR+, HER2-). Fourteen years postoperatively, she experienced a recurrence, and 1 month later, rapidly progressive dysphagia developed, resulting in the diagnosis of esophageal metastasis. Case 3:An 81-year-old woman was diagnosed with stage Ⅳ(bone)invasive ductal carcinoma(ER+, PgR+, HER2-)at age 73. After 8 years of systemic treatment, esophageal metastasis was diagnosed. In Cases 1 and 3, radiation therapy was selected, leading to symptomatic improvement and maintenance of oral intake until death. In contrast, Case 2, complicated by interstitial pneumonia, was treated with chemotherapy, but symptoms did not improve, and the patient remained unable to take food orally until death.