[A Case of Gallbladder MALT Lymphoma]

Area of Science:

• Gastroenterology
• Surgical Pathology
• Oncology

Background:

• Gallbladder MALT lymphoma is a rare malignancy.
• It often lacks typical imaging findings, making preoperative diagnosis challenging.

Purpose of the Study:

• To report a case of MALT lymphoma of the gallbladder.
• To emphasize the significance of histopathological examination in diagnosing rare gallbladder lesions.

Main Methods:

• A 64-year-old woman with gallbladder disease underwent laparoscopic cholecystectomy.
• Histopathological analysis of the resected gallbladder specimen, including immunohistochemistry (CD20, CD79a), was performed.

Main Results:

• The gallbladder specimen revealed a mucosal lesion consistent with MALT lymphoma.
• Immunohistochemistry confirmed the B-cell origin of the proliferating lymphocytes.
• The patient remained disease-free for 2 years post-resection.

Conclusions:

• MALT lymphoma of the gallbladder requires thorough pathological evaluation for diagnosis.
• Surgical resection can be an effective treatment for localized gallbladder MALT lymphoma.
• Postoperative histopathological review is crucial for identifying rare gallbladder malignancies.