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[Primary Squamous Cell Carcinoma of the Small Intestine-A Case Report]
Toshiya Miyata1, Yusuke Asada, Kentaro Asako
1Dept. of Surgery, Teikyo University School of Medicine.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|January 17, 2026
Summary
This case study details a rare instance of primary small intestinal squamous cell carcinoma without adenocarcinoma components. The 70-year-old female patient presented with abdominal pain and anemia, ultimately succumbing to the rare cancer.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Primary squamous cell carcinoma (SCC) of the small intestine is exceptionally rare.
- This condition is even less common in patients lacking adenocarcinoma components.
Purpose of the Study:
- To report a unique case of primary small intestinal SCC.
- To conduct a brief literature review on this rare entity.
Main Methods:
- Case presentation of a 70-year-old female with suspected sigmoid colon tumor.
- Diagnostic workup included computed tomography (CT), tumor marker analysis (SCC antigen), endoscopy, and biopsy.
- Surgical intervention involved palliative exploratory laparotomy with tumor resection.
Main Results:
- CT revealed a tumor involving the sigmoid colon, small intestine, and left adnexa with metastasis.
- Biopsy confirmed squamous cell carcinoma; pathological diagnosis was primary small intestinal SCC with no adenocarcinoma.
- Patient opted for best supportive care and died 6 months post-surgery.
Conclusions:
- Primary small intestinal SCC is a rare diagnosis requiring thorough investigation.
- This case highlights the importance of comprehensive pathological examination to differentiate primary tumors from metastatic disease.
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