[A Case of Multiple Liver Metastases from Breast Cancer Treated with Sacituzumab Govitecan Using a Scalp Cooling...

The patient was a 51-year-old woman who underwent surgery for bilateral breast cancer in 2021. In 2023, 2 years after surgery, multiple liver metastases were detected. Although she was treated with paclitaxel(PTX)plus bevacizumab(Bev), followed by pembrolizumab(Pemb)in combination with carboplatin(CBDCA)and gemcitabine(GEM), the liver metastases showed progressive disease. Sacituzumab govitecan was initiated as a third-line therapy in December 2024. At that time, a scalp cooling system was used, resulting in hair loss equivalent to CTCAE Grade 1. The patient did not require a wig, and the scalp cooling system demonstrated a favorable hair preservation effect. Further case accumulation is necessary to evaluate the hair loss prevention effect of the scalp cooling system during sacituzumab govitecan administration.