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Rest-Activity Rhythms and Suicidal Ideation in Pediatric Bipolar Disorder.

T H Stanley Seah1, Tina R Goldstein2,3, Noelle Rode2

  • 1Department of Psychology, College of Arts and Science, Miami University, Oxford, Ohio, USA.

Bipolar Disorders
|January 17, 2026
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Summary

Consistent daily activity patterns in youth with bipolar disorder (BD) are linked to lower suicidal ideation (SI). Maintaining stable rest-activity rhythms may be key for suicide risk detection and intervention in this population.

Keywords:
actigraphyadolescencebipolar disordercircadian rhythmsuicide

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Chronobiology

Background:

  • Youth with bipolar disorder (BD) have a significantly higher risk for suicidal ideation (SI).
  • Circadian rhythm disruptions, specifically 24-hour rest-activity patterns (RARs), are implicated in SI risk but are understudied in BD youth.
  • Understanding these patterns is crucial for developing targeted interventions.

Purpose of the Study:

  • To investigate the association between actigraphy-derived rest-activity rhythms (RARs) and suicidal ideation (SI) severity in adolescents with BD.
  • To identify specific RAR metrics that correlate with SI severity in this vulnerable population.

Main Methods:

  • A cross-sectional study involving 54 youth (aged 12-18) diagnosed with BD.
  • Daily wrist actigraphy was used to collect data on rest-activity patterns over 6 to 29 days.
  • Statistical analyses examined the relationship between RAR variables and self-reported SI severity, controlling for covariates like age, BD subtype, and medication use.

Main Results:

  • Greater interdaily stability in rest-activity patterns was significantly associated with lower SI severity.
  • Higher average activity levels during wakefulness were also linked to reduced SI severity.
  • These findings remained significant after controlling for relevant covariates.

Conclusions:

  • More consistent and stable daily activity patterns are associated with a lower risk of suicidal ideation in youth with BD.
  • Rest-activity rhythms (RARs) show potential as a measurable marker for suicide risk assessment and intervention strategies in this demographic.
  • Further research into RARs could inform novel therapeutic approaches for BD youth.