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Updated: Jan 20, 2026

A Molecular Readout of Long-term Olfactory Adaptation in C. elegans
Published on: December 22, 2012
The Adaptive Proximal Scaphoid Implant: Long-Term Follow-Up
Massimo Corain1, Andrea Colombo1, Umberto Lavagnolo1,2
1University Hospital of Verona (AOUI), Italy.
Background:
Scaphoid proximal pole fracture with avascular necrosis is a surgical challenge, particularly in patients with high functional demand. An option is the pyrocarbon adaptive proximal scaphoid implant (APSI), replacing the necrotic proximal pole.
Methods:
A long-term follow-up study of the early cases treated in our department was conducted. Thirty-six patients with a median follow-up time of 19 years (range, 11-25) were included in the analysis, performing clinical and radiological evaluations.
Results:
Clinically, significant improvements were observed in mean pain Numeric Rating Scale (from 6.8 [SD 2.1] to 2 [2]), range of motion, grip strength measured with the Jamar dynamometer (from 18 [8] kg to 24 [9] kg), Disabilities of the Arm, Shoulder, and Hand score (from 66 [6.5] to 13.7 [6.4]), and Patient-Rated Wrist Evaluation score (from 73 [10] to 28 [12]). Radiographs showed good implant stability. No patient required implant removal.
Conclusion:
The APSI prosthesis proves effective long term in relieving pain, improving function, and preventing carpal collapse through stable biomechanical integration.
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