Point-of-care testing in ischemic stroke

Ischemic stroke (IS) is a major cause of death and long-term disability worldwide, placing a significant burden on patients, families, and healthcare systems. Given the increasing incidence and the trend toward younger patients worldwide, early diagnosis and precision control are essential. Imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) are standard; however, their large footprint and need for specialist interpretation preclude on-site use. Point-of-care testing (POCT) has emerged as a rapid, user-friendly, and cost-effective alternative for near-patient detection. However, despite advancements, the clinical application of POCT remains limited due to technological, regulatory, and economic barriers. The implementation of rapid POCT for diagnosis and monitoring holds substantial potential to improve stroke care pathways and patient outcomes. Previous research has inadequately explored the intersection of POCT and IS, lacking foresight and practical applicability. This article aims to synthesize recent progress in POCT applications for IS diagnosis, therapeutic monitoring, and precision medication, highlighting its potential to enhance patient prognosis and optimize healthcare systems.