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Updated: Jan 20, 2026

Preparation and Respirometric Assessment of Mitochondria Isolated from Skeletal Muscle Tissue Obtained by Percutaneous Needle Biopsy
Published on: February 7, 2015
Threading the needle: Tips and tricks for challenging percutaneous abdominopelvic biopsies
Virginia B Planz1, Jennifer Huang1, Malak Itani2
1Vanderbilt University Medical Center, Department of Radiology and Radiological Sciences, Nashville, TN, USA.
Interventional radiologists can improve success rates for challenging percutaneous biopsies by using advanced imaging guidance and specialized techniques. These strategies enhance patient safety and diagnostic yield in personalized oncologic care.
Area of Science:
- Interventional Radiology
- Oncologic Imaging
- Percutaneous Procedures
Background:
- Personalized oncologic care increasingly relies on biomarker testing, driving demand for percutaneous biopsies.
- Complex and repeated abdominal biopsies present significant challenges for interventional radiologists.
- Careful assessment of feasibility, safety, and patient risk tolerance is crucial for challenging biopsies.
Purpose of the Study:
- To provide practical tips and tricks for performing challenging percutaneous biopsies.
- To outline strategies for optimizing success in image-guided biopsies.
- To address the growing need for complex biopsies in interventional radiology.
Main Methods:
- Review of current strategies for challenging percutaneous biopsies.
- Discussion of image guidance modality selection and patient comfort measures.
- Exploration of specialized techniques including IV contrast, navigation tools, and needle modifications.
Main Results:
- Leveraging imaging modality advantages can improve biopsy success.
- Ensuring patient comfort is a key factor in procedure management.
- Specialized techniques like IV contrast and navigational tools enhance procedural outcomes.
Conclusions:
- Implementing specific strategies can optimize the success of challenging percutaneous biopsies.
- Interventional radiologists can enhance diagnostic yield and patient safety through refined techniques.
- This review offers practical guidance for complex biopsy procedures in oncologic care.
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