Related Experiment Video
Updated: Jan 20, 2026

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
Published on: October 10, 2016
Synthesis and Functionalization of π-Extended [7]Carbohelicene
Qing-Yue Song1, Zuping Xiong2, Guiyi Yang1
1Guangdong Basic Research Center of Excellence for Aggregate Science, School of Science and Engineering, The Chinese University of Hong Kong (Shenzhen), Shenzhen, Guangdong, China.
None:
Helicenes represent a unique class of chiral molecular scaffolds with significant potential in multifunctional materials. Herein, we report the efficient synthesis and characterization of a novel [7]helicene derivative, [7]-OTf, bearing reactive triflate groups. X-ray crystallography confirms the helical structure and enantiomer stacking of [7]-OTf, while a high racemization barrier of 46.5 kcal·mol-1 enables the chiral separation by high-performance liquid chromatography. [7]-OTf exhibits green emission (λem = 487 nm) with a quantum yield of 20% and mirror-image chiroptical responses. Importantly, post-synthetic modification was successful via Sonogashira coupling. This work establishes [7]-OTf as a versatile and modifiable platform for advanced chiral materials.
Related Concept Videos
Synthesis and Functions of Calcitonin
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
10:53Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
π Molecular Orbitals of 1,3-Butadiene
The simplest conjugated diene is 1,3-butadiene: a four-carbon system where each carbon is sp2-hybridized and has an unhybridized p orbital that contains an unpaired electron. According to molecular orbital theory, atomic orbitals combine to form molecular orbitals such that the number...
11:27Synthesis and Characterization of Functionalized Metal-organic Frameworks
05:17Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
π Molecular Orbitals of the Allyl Radical
The allyl systems have identical molecular orbitals but differ in the number of π electrons....

