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Updated: Jan 20, 2026

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases
Published on: February 24, 2018
High-Concentration Hydrogen Peroxide Gels Containing Calcium Polyphosphate Associated With Violet Led Light:
Hemanuelly Albuquerque Dos Anjos1, Débora Alves Nunes Leite Lima1, Carolina Meneghin Barbosa1
1Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, São Paulo, Brazil.
Calcium polyphosphate (CaPP) in bleaching gels improved enamel hardness and maintained whitening effects. Violet LED light (VL) further boosted CaPP-enhanced bleaching, offering a promising dental treatment.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Photochemistry
Background:
- In-office bleaching with hydrogen peroxide (HP) can compromise tooth enamel integrity.
- Additives like calcium polyphosphate (CaPP) and calcium gluconate (GU) are explored to mitigate these effects.
- Violet LED light (VL) is investigated as an adjunct to enhance bleaching efficacy.
Purpose of the Study:
- To assess the impact of CaPP and GU on the efficacy and enamel properties of HP bleaching gels.
- To evaluate the synergistic effect of VL irradiation with these supplemented bleaching agents.
Main Methods:
- Bovine enamel blocks were treated with HP gels (commercial, with GU, or with CaPP) and their VL-irradiated counterparts.
- Bleaching efficacy was measured via color change (ΔEab, ΔE00).
- Enamel microhardness (KHN), surface microhardness loss (%SHL), and roughness (ΔRa) were assessed pre- and post-treatment and after 14 days. SEM evaluated surface morphology.
Main Results:
- VL irradiation alone showed minimal color change.
- CaPP significantly increased ΔE00 in VL-irradiated groups.
- Only CaPP- and GU-containing gels restored initial microhardness by day 14.
- CaPP groups exhibited reduced surface microhardness loss compared to controls.
Conclusions:
- Bleaching gels formulated with CaPP effectively maintained bleaching outcomes and promoted enamel microhardness recovery.
- VL irradiation enhanced the bleaching performance of CaPP-containing gels.
- CaPP is a promising additive for dental bleaching formulations, aiding remineralization and improving efficacy with VL.
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