Additive manufacturing in nano drug delivery systems

Area of Science:

• Pharmaceutical Sciences
• Biotechnology
• Materials Science

Background:

• Innovative fabrication technologies are driving advancements in nano-drug research.
• Nanoparticles are increasingly utilized as drug carriers, with significant research interest.
• Three-dimensional (3D) printing, an additive manufacturing (AM) technology, offers novel approaches to nanoparticle preparation.

Purpose of the Study:

• To review the applications of AM in nano drug delivery systems (NDDS).
• To highlight how AM can improve drug release kinetics, therapeutic efficacy, and reduce side effects.
• To discuss the potential of AM in personalized medicine and regenerative medicine.

Main Methods:

• Review of current literature on additive manufacturing (AM) and nanotechnology in drug delivery.
• Analysis of the benefits and challenges of using AM for nano drug delivery systems (NDDS).
• Exploration of research activities and potential solutions in the integration of AM and nanotechnology.

Main Results:

• AM, particularly nanoscale 3D printing, facilitates the creation of intricate structures for nanomedicine.
• AM enables patient-specific formulations, ushering in an era of personalized medicine.
• AM enhances drug release kinetics, improves therapeutic efficacy, and minimizes adverse effects.

Conclusions:

• Additive manufacturing (AM) holds transformative potential for the pharmaceutical industry and regenerative medicine.
• Further development of AM in nanotechnology can address complex healthcare challenges and advance drug delivery.
• Addressing scalability, biocompatibility, and regulatory concerns is crucial for the widespread adoption of AM in NDDS.