Recent progresses in combination cancer therapy using cyanine dye-based nanoparticles.

Area of Science:

• Biomaterials Science
• Nanotechnology
• Oncology

Background:

• Traditional cancer treatments like surgery, radiotherapy, and chemotherapy have limitations.
• Emerging therapies include photodynamic, photothermal, and sonodynamic approaches.
• Novel and efficient cancer treatment protocols are highly desirable.

Purpose of the Study:

• To review recent advances in cyanine nanoparticle-based cancer combination therapy (2018-2023).
• To emphasize cyanine dye structures, design concepts, and combination strategies.
• To discuss challenges and future clinical applications.

Main Methods:

• Literature review of studies published between 2018 and 2023.
• Focus on cyanine nanoparticles assembled from cyanine dyes and polymers/liposomes.
• Analysis of combination therapy strategies and their efficacy.

Main Results:

• Cyanine nanoparticles exhibit high biocompatibility and long circulation times.
• These nanoparticles are effective in various cancer combination therapy systems.
• Significant progress has been made in the design and application of these systems.

Conclusions:

• Cyanine nanoparticles represent a powerful tool for cancer combination therapy.
• Further research into their structures and combination strategies can enhance treatment outcomes.
• This field holds potential for future clinical translation and improved cancer patient care.