Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Folding01:22

Protein Folding

126.5K
Overview
126.5K
Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish08:00

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish

15.3K
Imaging of cerebrovascular development in larval zebrafish is described. Techniques to facilitate 3D imaging and modify cerebrovascular development using chemical treatments are also provided.
15.3K
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

4.1K
Here, we present detailed surgical procedures for endoscopic bilateral nipple-sparing mastectomy via a single axillary incision with immediate pre-pectoral implant-based breast reconstruction. This procedure is a secure and viable method for breast cancer...
4.1K
Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

17.8K
This article describes a method to obtain a three-dimensional (3D) structure of helically assembled molecules using cryo-electron microscopy. In this protocol, we use HIV-1 capsid assemblies to illustrate the detailed 3D reconstruction procedure for achieving a density map by the iterative helical real-space reconstruction...
17.8K
A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery08:05

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

7.8K
Here, we describe a pre-clinical animal model for studying the pathophysiology of ischemia-reperfusion injury in reconstructive microsurgery. This free skin flap model based on the superficial caudal epigastric vessels in the rat may also allow for the evaluation of different therapies and compounds to counteract ischemia-reperfusion injury-related...
7.8K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

19.6K
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
19.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrative systematic review and transcriptomic -machine learning analysis of molecular signatures in metaplastic breast cancer.

Ecancermedicalscience·2026
Same author

National United Kingdom study of the management of breast cancer locoregional recurrence (MARECA) study: Analysis of disease presentation and patient management.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Effect of COVID-19 NHS breast screening pause on breast cancer presentation and management: an insight into overdiagnosis.

JRSM open·2026
Same author

Comparative analysis of distinct genomic landscapes in young-onset gBRCA1/2 breast cancer.

JCI insight·2026
Same author

A Delphi consensus for implementing genomic testing in unresectable or metastatic urothelial cancer.

BJU international·2026
Same author

Outcomes of a joint paediatric breast clinic: an observational case series.

Archives of disease in childhood·2026

Related Experiment Video

Updated: Jan 20, 2026

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish
08:00

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish

Published on: April 22, 2014

15.3K

The inframammary fold: Structure, clinical considerations, and reconstructive techniques.

Camellia Richards1, Sonam Patel1, Hannah Markham2

  • 1Cancer Sciences, Faculty of Medicine, University of Southampton and University Hospital Southampton, Southampton, UK.

JPRAS Open
|January 19, 2026
PubMed
Summary

This review examines the anatomy and surgical reconstruction of the inframammary fold (IMF). It highlights challenges and debates in current literature, emphasizing the need for comparative studies on reconstructive techniques.

Keywords:
AnatomyBottoming-outDouble-bubbleGender-affirming surgeryInframammary foldReconstruction

More Related Videos

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.1K
Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

17.8K

Related Experiment Videos

Last Updated: Jan 20, 2026

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish
08:00

Imaging and 3D Reconstruction of Cerebrovascular Structures in Embryonic Zebrafish

Published on: April 22, 2014

15.3K
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

4.1K
Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

17.8K

Area of Science:

  • Plastic Surgery
  • Anatomy
  • Surgical Reconstruction

Background:

  • The inframammary fold (IMF) is crucial for breast shape and position.
  • Surgical disruption or reconstruction of the IMF presents significant challenges.
  • Current literature lacks direct comparisons of various IMF reconstruction methods.

Purpose of the Study:

  • To review the macro- and microscopic anatomy of the inframammary fold.
  • To discuss indications and procedures for IMF reconstruction.
  • To consider challenges in reconstructive techniques, gender-affirming surgery, and IMF pathologies.

Main Methods:

  • Literature review of anatomical and surgical studies on the inframammary fold.
  • Analysis of existing reconstructive techniques and their reported outcomes.
  • Discussion of evidence levels and sample sizes in current research.

Main Results:

  • The anatomy of the inframammary fold is complex and its relationship with thoracic landmarks impacts reconstruction.
  • Various reconstructive techniques exist but lack direct comparative evidence.
  • Challenges include differing techniques, gender-affirming surgery, and specific IMF insufficiencies.

Conclusions:

  • A comprehensive understanding of inframammary fold anatomy is essential for successful reconstruction.
  • Further research with direct comparisons of reconstructive techniques is needed.
  • Addressing specific challenges in IMF reconstruction is critical for optimal patient outcomes.