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Published on: October 31, 2019
First Reported Case of Prosthetic Joint Infection Caused by an Unusual Bacterium: Neisseria macacae
Yeşim Beşli1, Sinem Öktem Okullu2, Yasemin Gündoğdu3
1Department of Microbiology, American Hospital, İstanbul, Türkiye.
Abstract:
Acute non-traumatic joint pain, swelling, and fever require prompt evaluation for a prosthetic joint infection, a serious bacterial complication affecting both large and small joints. Neisseria gonorrhoeae and Staphylococcus aureus are among the most common causes, typically involving a single joint. To the best of our knowledge, we report the first case of a prosthetic joint infection caused by Neisseria macacae, highlighting its relevance for differential diagnosis. Identification was achieved using MALDI-TOF and confirmed with next-generation sequencing. While N. gonorrhoeae and Neisseria meningitidis are well-recognized pathogens, other Neisseria species may cause opportunistic infections, underscoring the importance of comprehensive microbiological evaluation.
Insights
This study reports the first prosthetic joint infection caused by Neisseria macacae, a rare bacterial pathogen. Prompt evaluation is crucial for prosthetic joint infections, even with unusual bacteria like N. macacae.
Area of Science:
- Infectious Diseases
- Microbiology
- Orthopedics
Background:
- Prosthetic joint infections (PJIs) present with acute joint pain, swelling, and fever.
- Common causative agents include Neisseria gonorrhoeae and Staphylococcus aureus, typically affecting a single joint.
- Differential diagnosis for PJIs is critical for effective treatment.
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