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Updated: Jan 20, 2026
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Impact of Real-Time Multiplex PCR Testing for Respiratory Viruses on Antibiotic Use
Zeynep Tekin-Taş1, Hasan Selçuk Özger1, Fidan Sultanova1
1Department of Infectious Diseases and Clinical Microbiology, Gazi University School of Medicine, Ankara, Türkiye.
Objective:
Real-time multiplex polymerase chain reaction (PCR) test increases the detection of viral respiratory tract infections. This study aimed to evaluate the effect of real-time multiplex PCR on antibiotic use in viral respiratory tract infections.
Materials And Methods:
This retrospective study included patients who underwent respiratory multiplex PCR tests. Patients were grouped into influenza-like illness, viral pneumonia, bacterial pneumonia, and co-infection. These groups were compared in terms of antibiotic use.
Results:
This retrospective study included patients who underwent respiratory multiplex PCR tests. Patients were grouped into influenza-like illness, viral pneumonia, bacterial pneumonia, and co-infection. These groups were compared in terms of antibiotic use.
Conclusion:
Despite a confirmed viral etiology by PCR, antibiotic use remained high, particularly in cases of viral pneumonia. These findings underscore the need for targeted antimicrobial stewardship interventions, including clinician education and integration of diagnostic-therapeutic approaches, to optimize antibiotic prescribing in respiratory infections.
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