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Updated: Jan 20, 2026
Interslice Magnetization Transfer Ratio Imaging for Meningioma Detection
Published on: May 30, 2025
Case report: preoperative radiological suspicion of atypical meningioma: A diagnostic challenge
Raisa Mahmudah1, Namira Ammarin1, Tasiya Ocvianty1
1Department of Radiology, Faculty of Medicine, Universitas Padjadjaran, West Java, Indonesia.
Abstract:
Atypical meningiomas represent a minority of intracranial meningiomas yet carry more aggressive biological behavior and higher recurrence rates, making preoperative differentiation essential for optimal management. We report a 56-year-old female presenting with progressive headaches, drowsiness, and vomiting, with no focal neurological deficits. Brain Magnetic Resonance Imaging (MRI) revealed a dural-based lesion at the posterior falx with cystic components, irregular margins, heterogeneous enhancement, disproportionate peritumoral edema, all suggesting atypicality. Subtotal resection followed by histopathological analysis confirmed a atypical meningioma. This case underscores the pivotal role of comprehensive MRI-including conventional sequences and advanced techniques-in identifying features of atypical meningioma even without definitive brain invasion, thereby guiding appropriate surgical planning and consideration of adjuvant therapy.
Insights
Preoperative Magnetic Resonance Imaging (MRI) is crucial for identifying atypical meningiomas, which are aggressive brain tumors. Recognizing specific MRI features aids in surgical planning and treatment for these challenging intracranial lesions.
Area of Science:
- Neurosurgery
- Neuroradiology
- Oncology
Background:
- Atypical meningiomas are rare but aggressive intracranial tumors with high recurrence rates.
- Preoperative differentiation between typical and atypical meningiomas is critical for patient management.
- Current diagnostic challenges necessitate improved methods for identifying aggressive meningioma subtypes.
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