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Published on: July 5, 2022
Post-COVID-19 Inflammatory Myopathy With Dermatomyositis-Mixed Connective Tissue Disease (MCTD) Overlap Features and
Nicholas Lorenz1, Amia Mourad2, Grant Weiderman3
1Orthopaedic Surgery, Lake Erie College of Osteopathic Medicine (LECOM) - Bradenton, Bradenton, USA.
None:
Autoimmune inflammatory myopathies can emerge after viral illnesses and may present with a wide range of neuromuscular and systemic symptoms. Post-viral immune dysregulation may unmask or trigger overlap syndromes characterized by muscle inflammation, dysphagia, airway involvement, and broader immune activation. This report describes a case of inflammatory myopathy with dermatomyositis and mixed connective tissue disease-associated antibodies occurring after a recent COVID-19 infection, highlighting the diagnostic challenges and severity of presentation. The case underscores the importance of recognizing post-COVID autoimmune complications and initiating timely immunosuppressive therapy to reduce long-term morbidity.
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