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Updated: Jan 20, 2026

Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism
Published on: January 12, 2019
Advanced Metabolic-Guided Perfusion Concepts in an Obese Patient Undergoing Cardiac Surgery: A Case Report
Ali Civelek1, Alireza Soltanzadeh2, Maryam Alizadegan2
1Department of Cardiovascular Surgery, Okan University Hospital, Istanbul, TUR.
This case study highlights how indexed oxygen delivery (DO₂i) monitoring, adjusted for temperature, can guide cardiopulmonary bypass (CPB) in obese patients. This strategy helped maintain stable oxygen delivery and ensure uncomplicated recovery in a high-risk patient.
Area of Science:
- Cardiology
- Anesthesiology
- Critical Care Medicine
Background:
- Obesity increases metabolic demands and reduces tolerance to hemodilution during cardiopulmonary bypass (CPB).
- Adequate indexed oxygen delivery (DO₂i) is crucial for obese patients undergoing cardiac surgery, but evidence on DO₂i-guided perfusion is limited.
- Redo cardiac surgery in obese patients presents unique challenges due to elevated oxygen requirements and potential for oxygen-delivery instability.
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