Progressive Metastatic Cutaneous TFCP2::FUS Fusion-Positive Rhabdomyosarcoma: A Case Report.

Dustine Reich1, Fabrizio Remotti2, Esperanza Villanueva-Siles3

  • 1Weill Cornell Medicine, New York, NY, USA.

Case Reports in Oncology
|January 19, 2026
PubMed
Summary

This rare case of aggressive rhabdomyosarcoma (RMS) with a TFCP2::FUS gene fusion presented with multiple skin lesions and visceral metastases. The cancer showed resistance to multiple treatments, including chemotherapy, immunotherapy, and radiation.

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